Course materials

pKa Tables: pKa Evans PDF pKa2 PDF pKa3 PDF

ORGANIC CHEMISTRY ACRONYMS

Named Reactions used in the course

Top-pharmaceuticals-poster

Presentations - in class lectures

 

Week
Topics
Handouts
1

Heterocycles

VTOC

PDF Heterocyclic PDF

PDFexercisesKey

2

Biological Chemistry and Chemistry of Life

VTOC_Lipids
VTOC_Carbohydrates

VTOC_aminoacids

VTOC_DNA

Lipids1Lipids2

Carbohydrates

Aminoacids_petides_DNA

Chemistry of Life

PDFexercises

 

3

Chemistry and Stereochemistry of Life

 

Advances Stereochemistry

VTOC_Symmetry Elements

VTOC_Stereoselective reactions

 


Chemistry and Stereochemistry of Life

 

Symmetry in Organic Chemistry

SOC_expl

Chirality

Sym_Chi_mixed

Mixed_expl

Exercise1Esercise2

Privileged Chiral Ligands&Catalysts

Stereoselective reactions

 

Stereochemistry

 

4

Modern Organic Reactions (Oxidation)

VTOC_Oxidation

Modern Organic Reactions (Reduction)

VTOC_Reduction

Oxidation

Reduction

Enantio_RED&OX

Exercises0304

5-6

Modern Organic Reactions (Redox Neutral reactions )

VTOC_Anionic Rearrangements

Redox Neutral reactions

Exercises

5-6

Modern Organic Reactions (Carbenes and Nitrenes)

VTOC_Rearrangements to Electron Deficient Heteroatoms

Carbenes_nitrenes

Exercises

7

Modern Organic Reactions (Advanced functional group tranformations)

Stereoselective Aldol reaction

Advanced functional group tranformations

Coupling reagents

Olefination reactions

Aldol reactions

Allylation reactions

8-9

Modern Organic Reactions (Peryciclic reactions )

VTOC_Peryciclic Reactions

Peryciclic reactions1

Peryciclic reactions2

Exercises

10-11

Modern Organic Reactions (Organometallics)

VTOC_Organometallic

APPLICATIONS OF TRANSITION METAL CATALYSIS IN DRUG DISCOVERY AND DEVELOPMENT

Organometallics

Exercises

Organolithium_reagents

Lithium-Halogen Exchange

Directed_Ortho_Metalation

Magnesium-Halogen_Exchange

Suzuki_Reaction

Heck

Olefin_Metathesis

12

Modern Organic Reactions (Protecting groups)

VTOC_protectivegroups

Protecting groups

Mayers_protective_groups

12

Synthesis and Key Concepts in RetroSynthesis

VTOC_An Introduction to Synthesis

VTOC_Principles of Organic Synthesis

VTOC_Stereselective Synthesis

Synthesis

Natural product synthesis

Finding function and form